DoW Tick-Borne Disease Therapeutic/Diagnostic Research Award
<p><strong>Summary:</strong> The intent of the fiscal year 2026 (FY26) Tick-Borne Disease Research Program (TBDRP) Therapeutic/Diagnostic Research Award (TDRA) is to support product-driven therapeutic and diagnostic development research aimed at reducing the burden of Lyme disease and/or other tick-borne diseases and conditions, and improving patient care and/or quality of life. Treatment-focused applications should be therapeutic evaluation studies designed to advance new ideas aimed at drug or treatment discovery that are still in the early/preclinical stages of development. Diagnosis-focused applications should propose diagnostic approaches that will be readily integrated into clinical settings. <strong style="color: rgb(0, 176, 80);"><em> </em></strong></p><p><br></p><p><a href="https://cdmrp.health.mil/pubs/press/2026/tbdrppreann" target="_blank">https://cdmrp.health.mil/pubs/press/2026/tbdrppreann</a></p><p><br></p>
HT942526TBDRPTDRA
Award Ceiling
$2.6M
Closes
Oct 22, 2026
40d left
ROSES25: D.8 Habitable Worlds Observatory Precursor Science Investigation
<p><span style="color: red;">PLEASE NOTE: this program has MANDATORY Notices of Intent, which are due via NSPIRES by </span><u style="color: rgb(230, 0, 0);">September 10, 2026</u><span style="color: red;">. See the full posting on NSPIRES for details.</span></p> <p><br></p> <p><strong><span class="ql-cursor"></span>NOTICE: Corrected, August 28, 2026. The Open Science and Data Management Plan was added to Table D.8-1 in Section 3.4. New text is in bold. The due dates remain unchanged.</strong></p> <p><br></p> <p><strong>NOTICE:</strong> Amended July 27, 2026. This amendment presents a new program element in ROSES-2025. Mandatory NOIs (see Section 3.1) are due by September 10, 2026, and proposals are due by October 26, 2026. The 7-page limit to the S/T/M Section and required content of proposals to this program element differ in several ways from the defaults set in the ROSES-2025 Summary of Solicitation (see Section 3).</p> <p><br></p> <p><strong>NOTICE:</strong> Research security training required starting August 5, 2026. All PIs and any Co-Is that would spend ≥ 10% time on a proposed grants or cooperative agreements must certify they have taken research security training. NASA will be satisfied with the four online research security training modules on the National Science Foundation's (NSF) Research Security Training website at https://www.nsf.gov/research-security/training or the SECURE Center condensed version of the four modules at https://www.secure-center.org/ctm</p> <p><br></p> <p><span style="color: black;">This synopsis is a generic summary that is posted for each of the many individual "program elements" in NASA’s Research Opportunities in Space and Earth Sciences (ROSES) – 2025 solicitation. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables </span><a href="https://solicitation.nasaprs.com/ROSES2025table2" target="_blank">2</a><span style="color: black;"> or </span><a href="https://solicitation.nasaprs.com/ROSES2025table3" target="_blank">3</a><span style="color: black;"> of ROSES at </span><a href="https://solicitation.nasaprs.com/ROSES2025table2" target="_blank">https://solicitation.nasaprs.com/ROSES2025table2</a></p> <p><span style="color: black;">and </span><a href="https://solicitation.nasaprs.com/ROSES2025table3" target="_blank">https://solicitation.nasaprs.com/ROSES2025table3</a><span style="color: black;">, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in the Solar System Science program (NNH25ZDA001N-SCUBED) one would follow </span><a href="https://nspires.nasaprs.com/external/solicitations/summary.do?solId=%7bC92A28D2-9E30-4149-24B7-8A40ED4F564B%7d&path=&method=init" target="_blank">the link to the NSPIRES page for that program element</a><span style="color: black;"> and then to read the text of the call one would click on “C.2 Solar System Science (.pdf)”</span><span style="color: purple;"> </span><span style="color: black;">to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “</span><a href="https://nspires.nasaprs.com/external/viewrepositorydocument?cmdocumentid=1036500&solicitationId=%7bC92A28D2-9E30-4149-24B7-8A40ED4F564B%7d&viewSolicitationDocument=1" target="_blank">C.1 Planetary Science Research Program Overview (.pdf)</a><span style="color: black;">” from that same page.</span> <span style="color: black;">While the letters and numbers are different for each element within ROSES (A.10, B.3, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. In 2025, </span>most program elements will be set up for application via Grants.gov only if requested at least 30 days in advance of the due date. For more on Grants.gov submissions see Section IV(b)v of the ROSES Summary of Solicitation, that may be found at <a href="https://solicitation.nasaprs.com/ROSES2025" target="_blank">https://solicitation.nasaprs.com/ROSES2025</a>.</p> <p><span style="color: black;"> </span></p> <p><span style="color: black;">The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2025 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 21, 2025. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology supported by SMD. </span>Awards will be made as grants, cooperative agreements, or contracts depending on the nature of the work proposed. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. Funded Co-Is at government labs will receive inter- or intra-agency transfers<span style="color: black;">. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables </span><a href="https://solicitation.nasaprs.com/ROSES2025table2" target="_blank">2</a><span style="color: black;"> and </span><a href="https://solicitation.nasaprs.com/ROSES2025table3" target="_blank">3</a><span style="color: black;">), a table that provides a very top level summary of proposal contents (</span><a href="https://nspires.nasaprs.com/external/viewrepositorydocument?cmdocumentid=1041499&solicitationId=%7b2A1D139B-B9C7-CE8C-2E81-223FD08460F9%7d&viewSolicitationDocument=1" target="_blank">Table 1</a><span style="color: black;">), and the full text of the ROSES-2025 "Summary of Solicitation", may all be found NSPIRES at </span><a href="https://solicitation.nasaprs.com/ROSES2025" target="_blank">https://solicitation.nasaprs.com/ROSES2025</a><span style="color: black;">.</span></p> <p><span style="color: black;"> </span></p> <p><span style="color: black;">Frequently asked questions for ROSES are posted at </span><a href="http://science.nasa.gov/researchers/sara/faqs/" target="_blank">http://science.nasa.gov/researchers/sara/faqs</a><span style="color: black;">. Questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: </span><a href="http://science.nasa.gov/researchers/sara/program-officers-list/" target="_blank">http://science.nasa.gov/researchers/sara/program-officers-list</a><span style="color: black;">. </span>General questions concerning ROSES-2025 may be directed to the office of the SMD Deputy Associate Administrator for Research at <span style="color: rgb(0, 0, 239);">sara@nasa.gov</span>.</p> <p><span style="color: black;"> </span></p> <p><span style="color: black;">Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at </span><a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__nspires.nasaprs.com_&d=DwMGaQ&c=ApwzowJNAKKw3xye91w7BE1XMRKi2LN9kiMk5Csz9Zk&r=2ixpkCCnNce056JoBL-BGFZPDe7JBWz4wpylXLQCS6s&m=50Vi0oUMclJgXKW1hUTR82Av51i56o31RG3n3UC9Cqg&s=U9bsGUTHAvBTDjSAoG5nnw63Lc9engudohcIe4r-h8U&e=" target="_blank">http://nspires.nasaprs.com</a><span style="color: black;"> and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2025 blog feed for amendments, clarifications, and corrections to at </span><a href="https://science.nasa.gov/researchers/solicitations/roses-2025/" target="_blank">https://science.nasa.gov/researchers/solicitations/roses-2025/</a>,<span style="color: black;"> and (3) The ROSES-2025 due date Google calendars (one for each science division). Instructions are at </span><a href="https://science.nasa.gov/researchers/sara/library-and-useful-links" target="_blank">https://science.nasa.gov/researchers/sara/library-and-useful-links</a><span style="color: black;"> (link from the words due date calendar).</span></p>
NNH25ZDA001N-HWOPSI
Award Ceiling
—
Closes
Oct 26, 2026
44d left
ONR FY27 NOFO for Young Investigator Program
<p>The Office of Naval Research Young Investigator Program seeks proposals addressing research areas (as described in the ONR Science and Technology Department section of ONR's website at https://www.onr.navy.mil) which are of interest to ONR Program Officers will be considered. Contact information for each division (a subgroup of an S&T Department) is also listed within the S&T section of the website.</p>
N0001426SF004
Award Ceiling
—
Closes
Oct 30, 2026
48d left
RESTORE Act Centers of Excellence Research Grants Program
<p>Treasury is publishing multiple funding opportunity notices for its RESTORE Act grant programs. This announcement applies only to the Centers of Excellence Research Grants Program.Trust Fund amounts are available to establish one or more Centers of Excellence through competitive subawards to nongovernmental entities and consortia in the Gulf Coast Region, including institutions of higher education. Funds may be used to establish Centers of Excellence, and by those Centers of Excellence for science, technology, and monitoring in one or more of the following disciplines as described in the RESTORE Act and Treasury’s implementing regulations at 31 CFR 34.704: 1) Coastal and deltaic sustainability, restoration, and protection, including solutions and technology that allow citizens to live in a safe and sustainable manner in a coastal delta in the Gulf Coast Region. 2) Coastal fisheries and wildlife ecosystem research and monitoring in the Gulf Coast Region. 3) Offshore energy development, including research and technology to improve the sustainable and safe development of energy resources in the Gulf of Mexico. 4) Sustainable and resilient growth, economic and commercial development in the Gulf Coast Region. 5) Comprehensive observation, monitoring, and mapping of the Gulf of Mexico.Eligible applicants issuing subawards to Center(s) of Excellence must establish and implement a program to monitor compliance with its subaward agreements.</p>
GR-RCE-25-001
Award Ceiling
$14.5M
Closes
Oct 31, 2026
49d left
CHIPS Incentives Program – Facilities for Semiconductor Materials and Manufacturing Equipment
<p>The CHIPS Incentives Program aims to catalyze long-term economically sustainable growth in the domestic semiconductor industry in support of U.S. economic and national security. This is the second Notice of Funding Opportunity under this program and seeks applications for projects for the construction, expansion, or modernization of commercial facilities for semiconductor materials and manufacturing equipment.</p> <p><br></p> <p>For more information, additional resources, and instructions on how to apply, please visit chips.gov. Note that all applications must be submitted through the CHIPS Incentives Portal at <a href="https://applications.chips.gov" target="_blank">https://applications.chips.gov</a>. If you have any questions on how to apply, please email apply@chips.gov.</p> <p><br></p>
2023-NIST-CHIPS-SMME-01
Award Ceiling
—
Closes
Nov 1, 2026
50d left
Topology
The Topology program supports research on algebraic topology, including chromatic, equivariant, motivic, and (un)stable homotopy, homology and cohomology theories; bordism and K-theory; topological manifolds; knots and links; geometric topology; differential topology; transformation groups; topological quantum field theories; contact and symplectic structures; infinity and model categories; and topological data analysis. Conferences Topology proposals for conferences, workshops, summer/winter schools, and similar activities must be submitted to PD 22-1267 using the "Conference" or “Travel” proposal type in research.gov. The program’ssubmission windows for conference/travel proposalsare September 1-30 and April 1-30. Proposals with budgets not exceeding $50,000 should be submitted during a submission window that occursat least six months prior to the event. Proposals with budget requests that exceed $50,000 should be submitted during a submission window that occursat least eight months prior to the event. Principal Investigators should carefully read the relevant sections of the PAPPG to obtain important information regarding the substance of such proposals and note the additional requirements for travel support requests for international events.
PD-22-1267
Award Ceiling
—
Closes
Nov 3, 2026
52d left
Geometric Analysis
The program in Geometric Analysis supports research on differential geometry and its relation to partial differential equations and variational principles; geometric methods in modern mathematical physics; symplectic geometry; geometric group theory; geometric data analysis; aspects of global analysis, including convex, complex, integral, and information geometries; and related geometric topics. Conferences <span>Geometric Analysis proposals for conferences, workshops, summer/winter schools, and similar activities must be submitted to PD 22-1265 using the "Conference" or “Travel” proposal type in research.gov.</span> The program’s submission windows for conference/travel proposals are September 1-30 and April 1-30. Proposals with budgets not exceeding $50,000 should be submitted during a submission window that occursat least six months prior to the event. Proposals with budget requests that exceed $50,000 should be submitted during a submission window that occursat least eight months prior to the event. Principal Investigators should carefully read the relevant sections of the PAPPG to obtain important information regarding the substance of such proposals and note the additional requirements for travel support requests for international events.
PD-22-1265
Award Ceiling
$8.8M
Closes
Nov 3, 2026
52d left
DoW Reconstructive Transplant, Concept Award
<p><strong>Summary:</strong> The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Concept Award supports the exploration of highly innovative new concepts or untested theories that address an important problem relevant to reconstructive transplantation. The Concept Award does not support <a href="https://ebrap.org/eBRAP/public/gai.htm?version=CD26_01#_Definition_List:~:text=or%20hardware%20procurement.-,Clinical%20Trial%3A,-As%20defined%20in" target="_blank">clinical trials</a>.</p> <p><strong>Distinctive Features:</strong><strong style="color: red;"> </strong></p> <p>· <strong>Innovation:</strong> Innovative research may introduce a new paradigm, challenge existing paradigms, examine existing problems from new perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative.</p> <p>· <strong>Relevance:</strong> Projects should address at least one of the FY26 RTRP Focus Areas.</p> <p>· <strong>Preliminary Data:</strong><span style="color: rgb(0, 176, 80);"> </span>Presentation of preliminary data is not allowed; however, applications should demonstrate the ability to achieve interpretable results. A rationale for the proposed work must be provided.</p> <p>· <strong>Early-Career Investigators: </strong>Early-career investigators are encouraged to apply. Investigators at or above the level of postdoctoral fellow are eligible to apply.</p> <p><br></p> <p><br></p>
HT942526RTRPCA
Award Ceiling
$600K
Closes
Nov 4, 2026
53d left
DoW Bone Marrow Failure, Idea Development Award
<p>Summary: The BMFRP Idea Development Award (IDA) is intended to support innovative ideas and high-impact approaches based on scientifically sound evidence to move toward the BMFRP’s vision of understanding and curing BMF diseases.</p><p>Distinctive Features:</p><p><br></p><p>This funding opportunity is open to Established Investigators (EIs) and Early-Career Investigators (ECIs). Reviewers will assess Principal Investigators (PIs) using distinct review criteria based on their eligibility as an EI or ECI.</p><p><br></p><p>Preliminary data is not required. Applications should demonstrate the ability to achieve interpretable results in the absence of preliminary data supporting the hypothesis.</p>
HT942526BMFRPIDA
Award Ceiling
$4.0M
Closes
Nov 4, 2026
53d left
DoW Bone Marrow Failure, Resource Development Award
<p>Summary: The fiscal year 2026 (FY26) Bone Marrow Failure Research Program (BMFRP) Resource Development Award (RDA) supports the development of a multiomic atlas generated from well-annotated human bone marrow failure (BMF) samples, with omic data derived from marrow specimens. The resulting dataset should serve as an open-access, durable resource for the BMF research and clinical communities and is expected to facilitate key discoveries that advance the understanding of BMF diseases.</p><p><br></p><p>Distinctive Features: The application must include a robust Data Resource Sharing Plan that describes the means and timeline by which the fully developed resource will be made available to the scientific and clinical community.</p>
HT942526BMFRPRDA
Award Ceiling
$1.3M
Closes
Nov 4, 2026
53d left
DoW Bone Marrow Failure, Investigator-Initiated Research Award
<p>Summary: Supports studies that further develop mature ideas, expand upon key discoveries, and have the potential to make significant advances in bone marrow (BMF) failure research and/or patient care. Investigator-Initiated Research Award (IIRA) applications may involve translational and clinical research including studies in preclinical models, research with human data and/or anatomical substances, and research with human subjects, as well as correlative studies associated with a clinical trial(s); however, this award mechanism does not support clinical trials. IIRA applications may also support Investigational New Drug (IND)-enabling efforts such as lead compound characterization, and assessments of formulation and stability, absorption, distribution, metabolism and excretion, dose/response and toxicology.</p><p><br></p><p>Distinctive Features:</p><p><br></p><p>This funding mechanism allows for a partnering Principal Investigator (PI). Only the initiating PI will submit a pre-application, but both PIs will need to submit full applications. The partnering PI application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.</p><p><br></p><p>This award mechanism requires preliminary data relevant to the proposed project. Applications can support clinical research studies; however, this mechanism does not allow clinical trials.</p><p><br></p>
HT942526BMFRPIIRA
Award Ceiling
$1.3M
Closes
Nov 4, 2026
53d left
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation
<p>NSF invests in scientific discoveries, technological breakthroughs, and transformative innovations that strengthen economic growth, enhance security, and improve the lives of Americans and people around the world. Our ability to support that mission requires a robust scientific and engineering (S&E) enterprise in the United States that allows scientists to innovate at the frontier. In addition to funding scientists, America needs next-generation scientific instrumentation that allows scientists to pursue new innovations. In many fields, it is critical that this new scientific instrumentation is developed in the United States.</p> <p>In support of this mission, NSF is initiating a pilot emphasis area for its<a href="https://seedfund.nsf.gov/our-program/"> SBIR/STTR programs</a> to invest in startups and small businesses that are specifically developing enabling technologies that include next-generation instrumentation, novel experimental platforms, and other scientific equipment to advance the frontiers of scientific discovery and strengthen the American scientific and engineering enterprise. This encompasses novel instrumentation necessary for the coming era of AI-driven discoveries. This pilot will prioritize investing in the necessary infrastructure to support entirely new fields of scientific discovery, making new technological breakthroughs and transformative applications possible. Through this approach, NSF will continue to lead in propelling the scientific enterprise to new frontiers.</p> <p>This pilot emphasis area for the NSF SBIR/STTR programs funds across enabling technology areas and market sectors in alignment with the above goals; the programs do not solicit specific technologies for the purpose of procuring goods and services for the agency from startups and small businesses.</p> <p>NSF will continue to invest in other deep-tech ventures through the historic NSF SBIR/STTR programs available here.</p> <p>Funding opportunities are available through the NSF SBIR/STTR programs: Phase I, Phase II, Fast-Track, and Supplements. Each company can receive up to $2.0 million for R&D. Separately, NSF welcomes Strategic Breakthrough proposals, upon recommendation from the Program Officer, for Phase II awardees. NSF takes no equity and awardees keep full ownership of their company and intellectual property.</p> <p><strong>Expanding Participation</strong><strong> in STEM and Gold Standard Science:</strong></p> <p>NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF also expects the highest standards of scientific rigor, integrity and adherence to tenets of <a href="https://www.nsf.gov/policies/gold-standard-science">Gold Standard Science</a> in proposals, as appropriate for the field of science and research modality.</p>
26-511
Award Ceiling
$40.0M
Closes
Nov 4, 2026
53d left
DoW Reconstructive Transplant, Investigator-Initiated Research Award
<p><strong>Summary:</strong> The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award supports studies that have the potential to make an important contribution to reconstructive transplant research, patient care, and/or quality of life. All projects must demonstrate solid scientific rationale with military-relevant utility. The Investigator-Initiated Research Award does not support <a href="https://ebrap.org/eBRAP/public/gai.htm?version=CD26_01#_Definition_List:~:text=or%20hardware%20procurement.-,Clinical%20Trial%3A,-As%20defined%20in" target="_blank">clinical trials</a>.</p> <p><br></p> <p><strong>Distinctive Features:</strong><strong style="color: red;"> </strong></p> <p>· <strong>Scope:</strong> Applications may focus on any phase of research from basic through translational, including preclinical studies in animal models, and clinical research in human subjects or human anatomical substances.</p> <p>· <strong>Study Design and Feasibility:</strong> The study design should be rigorous and support maximal reproducibility and translational feasibility. A strong statistical plan with appropriate power analysis is important.</p> <p>· <strong>Impact:</strong> Project results should have the potential for long- and short-term impact on the reconstructive transplant research field and/or patient community. Projects should address at least one of the FY26 RTRP Focus Areas.</p> <p>· <strong>Preliminary Data:</strong><span style="color: rgb(0, 176, 80);"> </span>Preliminary and/or published data that are relevant to reconstructive transplantation and support the rationale for the proposed research <strong>must be</strong> included.</p> <p>· <strong>Military Relevance: </strong>All projects must be responsive to the health care needs of military Service Members and/or Veterans recovering from traumatic injury, and/or their Family members, caregivers, or clinicians, as well as the general public. Collaboration with military researchers and clinicians is encouraged but not required.</p>
HT942526RTRPIIRA
Award Ceiling
$8.0M
Closes
Nov 4, 2026
53d left
SBE Postdoctoral Research Fellowships
The Directorate for Social, Behavioral and Economic Sciences (SBE) offers Postdoctoral Research Fellowships to encourageindependence earlyin the fellow'scareerby supporting his or herresearch and training goals.The research and training plan of each fellowship must address important scientific questions within thescope of the SBE directorate and the specific guidelines in this solicitation. The SPRF program offers two tracks: (I) Fundamental Research in the SBE Sciences (SPRF-FR) and (II) Broadening Participation in the SBE Sciences (SPRF-BP). See the full text of the solicitation for a detailed description of these tracks.
23-500
Award Ceiling
$170K
Closes
Nov 4, 2026
53d left
U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:
<p>The NSF State and Regional AI Infrastructure Hubs program aims to expand access to the compute required for AI-enabled scientific discovery and to transform the research, education, and training opportunities offered by institutions of higher education. AI Infrastructure Hubs will connect researchers to new compute infrastructure that leverages contributions from state governments, research institutions, industry, and philanthropy, accelerating AI-enabled discovery across science and engineering and developing a skilled technical workforce for AI use in the scientific enterprise. </p> <p>The program responds to a core tenet of <a href="https://www.whitehouse.gov/wp-content/uploads/2026/07/Science-A-New-Golden-Age.pdf"><em>Science: A New Golden Age</em></a> to renew America’s research and development (R&D) for changes in today’s scientific enterprise, including the role of AI in laying the foundation for a new era of scientific discovery and the growing role of industry and philanthropy in funding R&D. In response, the Administration’s <a href="https://www.whitehouse.gov/wp-content/uploads/2026/07/White-House-Fiscal-Year-2028-RD-Priorities-Memorandum.pdf">FY28 R&D Priorities Memorandum</a> called for investing in AI for science as a national mission and expanding the scale of, and flexible access to, advanced compute and data infrastructure that researchers now require for frontier scientific discovery.</p> <p>Each AI Infrastructure Hub will be organized as a flexible state or regional consortium of state and local governments, research institutions, philanthropies, and the private sector. Consortia will be responsible for all funding for new or expanded computing, data, and AI resources, whether on-premises or cloud-based. NSF will fund each Hub’s consortium coordination, AI infrastructure workforce development, and faculty training and coursework development in leveraging AI for science. </p> <p class="paragraph"> </p> <p><span class="normaltextrun"><span><span><span xml:lang="EN-US" data-contrast="auto"> </span></span></span></span></p>
26-513
Award Ceiling
$100.0M
Closes
Nov 4, 2026
53d left
Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)
<p>This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis.</p><p>The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis. </p><p>Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/digital/data">NSF data platforms</a>, the <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/funding/opportunities/idss-integrated-data-systems-services">NSF Integrated Data Systems and Services program</a>, the <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/focus-areas/ai/nairr">NSF-led National AI Research Resource</a>, the <a target="_blank" rel="noopener noreferrer" href="https://www.energy.gov/undersecretaryforscience/genesis-mission/genesis-mission">Genesis Mission platform</a>, or other national infrastructure.</p><p>NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets.</p><p><strong>Expanding Participation in STEM, NSF Priorities, and Gold Standard Science:</strong></p><p>NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fabout&data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498479654%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=%2FCCCSIR%2BbxoiV5%2B1TB7cvpsSDEm3xbBHiUwSHLExJao%3D&reserved=0">NSF's mission</a>. Proposers should review the list of <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fupdates-on-priorities&data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498507194%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=Q3GoODxs9MLDgKGJnSQEuvlBfoGApbPEekdS%2FoUtMoc%3D&reserved=0">NSF priorities</a> and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fpolicies%2Fgold-standard-science&data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498529191%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=FKjMYWT2h2O3dQGRYwuPLJiVjDlXeHhb4tlBf2W3DkE%3D&reserved=0">Gold</a> <a target="_blank" rel="noopener noreferrer" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fpolicies%2Fgold-standard-science&data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498548690%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=RbRtZB5wPjwz0gNaK8ypiBhqGbpAVBY2Agh5z7BpQTQ%3D&reserved=0">Standard Science</a> in proposals, as appropriate for the field of science and research modality.</p>
26-512
Award Ceiling
$100.0M
Closes
Nov 4, 2026
53d left
Fiscal Year (FY) 2027 Department of War (DoW) Defense University Research Instrumentation Program (DURIP)
<p>Department of Army:</p><p><br></p><p>The Department of War (DoW) announces the Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.</p>
W911NF26S0095
Award Ceiling
$3.0M
Closes
Nov 6, 2026
55d left
DoW Parkinson’s, Early Investigator Research Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Parkinson’s Research Program (PRP) Early Investigator Research Award (EIRA) supports Parkinson’s disease (PD) research for investigators in the early stages of their careers. The FY26 EIRA offers two funding levels, which align to the research career stage of the Principal Investigator (PI). Funding Level 1 (for fellows) requires the investigator to receive guidance from a designated Mentor, whereas Funding Level 2 (for early-career independent investigators) does not. Proposed research must address at least one of the four <u>FY26 PRP Focus Areas</u>.</p><p><strong>Distinctive Features:</strong></p><p>· The Early Investigator is considered the PI of the application and must exhibit strong potential for and commitment to pursuing a career as an investigator at the forefront of PD research; however, the PI is not required to have previous PD research experience.</p><p>· <strong>Funding Level 1: </strong>Applications must include at least one Mentor appropriate to the proposed research project who has experience in PD research and mentoring, as demonstrated by a record of active funding, recent publications, and successful mentorship. The selected Mentor(s) should also demonstrate a clear commitment to the development of the PI toward independence as a PD researcher. <strong><em>Preliminary data are encouraged but not required</em>.</strong></p><p>· <strong>Funding Level 2: </strong>Mentor not required. <strong><em>Preliminary data are required</em></strong>.</p><p>· Clinical trials are <strong><em>not </em></strong>allowed.</p>
HT942526PRPEIRA
Award Ceiling
$4.2M
Closes
Nov 6, 2026
55d left
Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP)
<p>The Department of Defense (DoD) announces the Fiscal Year 2027 Defense University Research Instrumentation Program (DURIP). DURIP is designed to improve the capabilities of accredited United States (U.S.) institutions of higher education to conduct research and to educate scientists and engineers in areas important to national defense, by providing funds for the acquisition of research equipment or instrumentation. For-profit organizations are not eligible for DURIP funding.</p>
NOFOAFRLAFOSR20260001
Award Ceiling
$7.0M
Closes
Nov 6, 2026
55d left
ROSES25: A.15 Biosphere
<p><strong style="color: red;">The close date above is the date for the Step-2 proposal due date. The Step-1 proposal due date is </strong><strong style="color: rgb(230, 0, 0);"><u>September 4, 2026</u></strong><strong style="color: red;">. Step-2 proposals cannot be submitted if a Step-1 proposal was not submitted.</strong></p> <p><br></p> <p><strong><span class="ql-cursor"></span>NOTICE: August 4, 2026. Going forward, a </strong><strong style="background-color: white; color: black;">$0.09/SBU charge now applies to </strong><strong>all </strong><strong style="background-color: white; color: black;">proposing to Earth Science (ROSES Appendix A) to use </strong><strong>any NASA high-end computing</strong><strong style="background-color: white; color: black;"> resource. Proposers must account for this in their budget, per the instructions provided in Section 7.3 of </strong><strong>ROSES-25 A.1 Earth Science Research Overview</strong><strong style="background-color: white; color: black;">.</strong><span style="background-color: white; color: black;"> </span></p> <p><br></p> <p><strong>NOTICE: Amended July 20, 2026. This amendment adds this new program element to ROSES-2025. This element uses a two-step proposal process (Section 4). Step-1 proposals are due by September 4, 2026, and Step-2 proposals are due November 6, 2026. Any proposal not preceded by an on-time compliant Step-1 proposal will be returned without review. The page limit for the S/T/M section of Step-2 proposals is 12 pages. Proposers to this program element are strongly encouraged to use the optional Earth Science Division template for the required summary table of work effort of the proposal; templates are available at https://science.nasa.gov/researchers/templates-for-earth-science-division-appendix-a-roses-proposals. Proposals submitted to this program will be evaluated using dual anonymous peer review, see Section 4.3 of this program element. </strong></p> <p><br></p> <p><strong>NOTICE: Research security training required starting August 5, 2026. All PIs and any Co-Is that would spend ≥ 10% time on a proposed grants or cooperative agreements must certify they have taken research security training. NASA will be satisfied with the four online research security training modules on the National Science Foundation's (NSF) Research Security Training website at https://www.nsf.gov/research-security/training or the SECURE Center condensed version of the four modules at https://www.secure-center.org/ctm</strong></p> <p><br></p> <p><strong> </strong><span style="color: black;">This synopsis is a generic summary that is posted for each of the many individual "program elements" in NASA’s Research Opportunities in Space and Earth Sciences (ROSES) – 2025 solicitation. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables </span><a href="https://solicitation.nasaprs.com/ROSES2025table2" target="_blank">2</a><span style="color: black;"> or </span><a href="https://solicitation.nasaprs.com/ROSES2025table3" target="_blank">3</a><span style="color: black;"> of ROSES at </span><a href="https://solicitation.nasaprs.com/ROSES2025table2" target="_blank">https://solicitation.nasaprs.com/ROSES2025table2</a></p> <p><span style="color: black;">and </span><a href="https://solicitation.nasaprs.com/ROSES2025table3" target="_blank">https://solicitation.nasaprs.com/ROSES2025table3</a><span style="color: black;">, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in the Solar System Science program (NNH25ZDA001N-SCUBED) one would follow </span><a href="https://nspires.nasaprs.com/external/solicitations/summary.do?solId=%7bC92A28D2-9E30-4149-24B7-8A40ED4F564B%7d&path=&method=init" target="_blank">the link to the NSPIRES page for that program element</a><span style="color: black;"> and then to read the text of the call one would click on “C.2 Solar System Science (.pdf)”</span><span style="color: purple;"> </span><span style="color: black;">to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “</span><a href="https://nspires.nasaprs.com/external/viewrepositorydocument?cmdocumentid=1036500&solicitationId=%7bC92A28D2-9E30-4149-24B7-8A40ED4F564B%7d&viewSolicitationDocument=1" target="_blank">C.1 Planetary Science Research Program Overview (.pdf)</a><span style="color: black;">” from that same page.</span> <span style="color: black;">While the letters and numbers are different for each element within ROSES (A.10, B.3, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. In 2025, </span>most program elements will be set up for application via Grants.gov only if requested at least 30 days in advance of the due date. For more on Grants.gov submissions see Section IV(b)v of the ROSES Summary of Solicitation, that may be found at <a href="https://solicitation.nasaprs.com/ROSES2025" target="_blank">https://solicitation.nasaprs.com/ROSES2025</a>.</p> <p><span style="color: black;"> </span></p> <p><span style="color: black;">The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2025 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 21, 2025. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology supported by SMD. </span>Awards will be made as grants, cooperative agreements, or contracts depending on the nature of the work proposed. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. Funded Co-Is at government labs will receive inter- or intra-agency transfers<span style="color: black;">. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables </span><a href="https://solicitation.nasaprs.com/ROSES2025table2" target="_blank">2</a><span style="color: black;"> and </span><a href="https://solicitation.nasaprs.com/ROSES2025table3" target="_blank">3</a><span style="color: black;">), a table that provides a very top level summary of proposal contents (</span><a href="https://nspires.nasaprs.com/external/viewrepositorydocument?cmdocumentid=1041499&solicitationId=%7b2A1D139B-B9C7-CE8C-2E81-223FD08460F9%7d&viewSolicitationDocument=1" target="_blank">Table 1</a><span style="color: black;">), and the full text of the ROSES-2025 "Summary of Solicitation", may all be found NSPIRES at </span><a href="https://solicitation.nasaprs.com/ROSES2025" target="_blank">https://solicitation.nasaprs.com/ROSES2025</a><span style="color: black;">.</span></p> <p><span style="color: black;"> </span></p> <p><span style="color: black;">Frequently asked questions for ROSES are posted at </span><a href="http://science.nasa.gov/researchers/sara/faqs/" target="_blank">http://science.nasa.gov/researchers/sara/faqs</a><span style="color: black;">. Questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: </span><a href="http://science.nasa.gov/researchers/sara/program-officers-list/" target="_blank">http://science.nasa.gov/researchers/sara/program-officers-list</a><span style="color: black;">. </span>General questions concerning ROSES-2025 may be directed to the office of the SMD Deputy Associate Administrator for Research at <span style="color: rgb(0, 0, 239);">sara@nasa.gov</span>.</p> <p><span style="color: black;"> </span></p> <p><span style="color: black;">Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at </span><a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__nspires.nasaprs.com_&d=DwMGaQ&c=ApwzowJNAKKw3xye91w7BE1XMRKi2LN9kiMk5Csz9Zk&r=2ixpkCCnNce056JoBL-BGFZPDe7JBWz4wpylXLQCS6s&m=50Vi0oUMclJgXKW1hUTR82Av51i56o31RG3n3UC9Cqg&s=U9bsGUTHAvBTDjSAoG5nnw63Lc9engudohcIe4r-h8U&e=" target="_blank">http://nspires.nasaprs.com</a><span style="color: black;"> and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2025 blog feed for amendments, clarifications, and corrections to at </span><a href="https://science.nasa.gov/researchers/solicitations/roses-2025/" target="_blank">https://science.nasa.gov/researchers/solicitations/roses-2025/</a>,<span style="color: black;"> and (3) The ROSES-2025 due date Google calendars (one for each science division). Instructions are at </span><a href="https://science.nasa.gov/researchers/sara/library-and-useful-links" target="_blank">https://science.nasa.gov/researchers/sara/library-and-useful-links</a><span style="color: black;"> (link from the words due date calendar). </span></p> <p><strong> </strong></p>
NNH25ZDA001N-BIOS
Award Ceiling
—
Closes
Nov 6, 2026
55d left