DoW, Peer Reviewed Cancer, Impact Award
<p>Summary: The fiscal year 2026 (FY26) Peer Reviewed Cancer Research Program (PRCRP) Impact Award supports mature research that will have a near-term impact on clinical cancer care in one of the congressionally directed FY26 PRCRP Topic Areas. Applicants must consider how the research project will lead to the advancement of knowledge in cancer research, patient care and/or treatment options in the Military Health System (MHS).</p><p><br></p><p>Distinctive Features:</p><p>• Applications must include preliminary data to support feasibility of the study.</p><p>• Projects must have strong potential to result in a near-term impact in cancer.</p><p>• The funding mechanism allows clinical trials.</p><p>• This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. Only the Initiating PI will submit a pre-application, but both PIs will need to submit full applications. The Partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, both applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.</p>
HT942526PRCRPIPA
Award Ceiling
$45.0M
Closes
Oct 5, 2026
23d left
American Alligators as Ecological Indicators of Everglades Restoration
<p>1) Note: A full study proposal and proposed budget are NOT requested at this time.</p><p><br></p><p>2) Project Title: American Alligators as Ecological Indicators of Everglades Restoration.</p><p><br></p><p>3) Brief Description of Anticipated Work: See Attached SOO for more information.</p><p><br></p><p>4) Period of Performance: Base period: 12 months from date of award. Follow-on (FO) periods: 4 12-month FO periods.</p><p><br></p><p>5) Please send responses or direct questions to:</p><p><br></p><p>Nicholas Aprea</p><p>Grants Specialist</p><p>USACE, Fort Worth District</p><p>Email: nicholas.a.aprea@usace.army.mil</p><p><br></p><p>Kathy Mitchell</p><p>Project Manager</p><p>USACE, Fort Worth District</p><p>Email: kathy.s.mitchell@usace.army.mil</p><p><br></p><p>6) Timeline for Review of Statements of Interest: 30 calendar days from date posted.</p>
W9126G262SOI9558
Award Ceiling
$1.5M
Closes
Oct 5, 2026
23d left
DoW Peer Reviewed Cancer, Idea Award
<p>Summary: The fiscal year 2026 (FY26) Peer Reviewed Cancer Research Program (PRCRP) Idea Award (IA) supports innovative, untested, high-risk/potentially high-reward concepts, theories, paradigms, and/or basic cancer research. The advancement of knowledge in cancer research, patient care, and/or treatment options in the Military Health System (MHS) is critical to Service Members, Veterans, other military beneficiaries and the American public.</p><p><br></p><p>Distinctive Features: The proposed project should demonstrate creative thinking and innovation.</p><p>• Incremental advances, the next logical step, or switching a model system from one cancer to another cancer are not appropriate for this award.</p><p>• Inclusion of preliminary data is not required; however, the project must be based on strong scientific rationale.</p><p>• New for FY26: Early Career Investigator Option: The Early Career Investigator option is designed to support the continued development of promising independent investigators that are early in their faculty appointments.</p>
HT942526PRCRPIA
Award Ceiling
$18.0M
Closes
Oct 5, 2026
23d left
American Crocodile Monitoring as an Indicator of Hydrologic Restoration in the Southern Estuaries for the U.S. Army Corps of Engineers, Jacksonville District.
<p>1) Note: A full study proposal and proposed budget are NOT requested at this time.</p><p><br></p><p>2) Project Title: American Crocodile Monitoring as an Indicator of Hydrologic Restoration in the Southern Estuaries for the U.S. Army Corps of Engineers, Jacksonville District.</p><p><br></p><p>3) Brief Description of Anticipated Work: See Attached SOO for this information.</p><p><br></p><p>4) Period of Performance: Base Period: 12 months from date of Award. Follow-on (FO) periods: (4) Four 12-month FO periods.</p><p><br></p><p>5) Please send responses or direct questions to:</p><p><br></p><p>Nicholas A. Aprea</p><p>Grants Specialist</p><p>USACE, Fort Worth District</p><p>Email: Nicholas.a.aprea@usace.army.mil</p><p><br></p><p>Nicole D. Baker</p><p>Project Manager</p><p>USACE, Fort Worth District</p><p>Email: Nicole.D.Baker@usace.army.mil</p><p><br></p><p>6) Timeline for Review of Statements of Interest: 30 calendar days from date posted.</p>
W9126G262SOI9486
Award Ceiling
$792K
Closes
Oct 5, 2026
23d left
Aquatic Fauna and Primary Production in the Florida Everglades
<p>1) Note: A full study proposal and proposed budget are NOT requested at this time.</p><p><br></p><p>2) Project Title: Aquatic Fauna and Primary Production in the Florida Everglades</p><p><br></p><p>3) Brief Description of Anticipated Work: See Attached SOO.</p><p><br></p><p>4) Period of Performance: Base period: 12 months from date of award. Follow-on (FO) periods: (4) four 12-month FO periods</p><p><br></p><p>5) Please send responses or direct questions to: </p><p><br></p><p>Nicholas Aprea</p><p>Grants Specialist</p><p>USACE, Fort Worth District</p><p>Email: nicholas.a.aprea@usace.army.mil </p><p><br></p><p>Kathy Mitchell</p><p>Project Manager</p><p>USACE, Fort Worth District</p><p>Email: kathy.s.mitchell@usace.army.mil </p><p><br></p><p>6) Timeline for Review of Statements of Interest: 30 calendar days from date posted.</p>
W9126G262SOI9557
Award Ceiling
$5.0M
Closes
Oct 5, 2026
23d left
Wading Bird Response to Ecosystem Restoration in Southwest Florida
<p>1) Note: A full study proposal and proposed budget are NOT requested at this time.</p><p><br></p><p>2) Project Title: Wading Bird Response to Ecosystem Restoration in Southwest Florida.</p><p><br></p><p>3) Brief Description of Anticipated Work: See attached SOO for this information.</p><p><br></p><p>4) Period of Performance: Base period: 12 months from date of award. Follow-on (FO) periods: (4) Four 12-month FO periods. Optional Task 5: Up to 24 months from date of award and Optional Task 6: 12 months from date of award.</p><p><br></p><p>5) Please send responses or direct questions to:</p><p><br></p><p>Nicholas Aprea</p><p>Grants Specialist</p><p>USACE, Fort Worth District</p><p>Email: nicholas.a.aprea@usace.army.mil</p><p><br></p><p>Emily Woodruff</p><p>Project Manager</p><p>USACE, Fort Worth District</p><p>Email: emily.t.woodruff@usace.army.mil</p><p><br></p><p>6) Timeline for Review of Statements of Interest: 30 calendar days from date posted.</p>
W9126G262SOI9597
Award Ceiling
$2.0M
Closes
Oct 5, 2026
23d left
Groundwater and Surficial Water Salinity Changes in Everglades National Park using Aerial Electromagnetic Surveys
<p><strong>NOTE:</strong> A complete study proposal and proposed budget are not requested at this time. </p><p><br></p><p><strong>NOTE:</strong> The established CESU indirect rate is 17.5%. For any Cooperative Agreement entered into in response to this RSOI, a maximum 17.5% indirect cost rate will be paid on work covered by such agreement or any modifications thereto. Unless the agreement specifies otherwise, the basis of direct costs against which the agreement’s indirect cost rate is applied must be either the same base identified in the recipient's federally negotiated indirect cost rate agreement or, if the recipient does not have a federally negotiated indirect cost rate agreement, the Modified Total Direct Cost (MTDC) base.</p><p><br></p><p><strong>TITLE OF PROJECT:</strong> Groundwater and Surficial Water Salinity Changes in Everglades National Park using Aerial Electromagnetic Surveys</p><p><br></p><p><strong>SYNOPSIS OF PROJECT:</strong> This project will support the U.S. Army Corps of Engineers (USACE) Jacksonville District by performing Aerial Electromagnetic (AEM) surveys to understand the current spatial extent and rate of saltwater intrusion in the ground and surface waters of the southern Florida Everglades. Results will be integrated with previous survey data conducted over the last 30 years to comprehend the impacts surrounding significant critical habitat loss. Future freshwater-saltwater interface trends will then be estimated to optimize management decisions tied to restoration efforts of the degraded wetland system.</p><p><br></p><p><strong>PERIOD OF PERFORMANCE</strong>: The Base Period of the agreement will extend 12 months from date of award. Four 12-month Follow-on Periods are anticipated based on availability of funding.</p><p><br></p><p><strong>SUBMISSION OF STATEMENT OF INTEREST</strong></p><p>• Statements of Interest (SOI) are due by Noon Central Time, 06 October 2026 via email to the parties listed below.</p><p>• Direct questions no later than Noon Central Time, 14 September 2026 via email to the parties listed below.</p><p>Cheryl R. Vendemia</p><p>Grants Specialist</p><p>USACE Fort Worth District</p><p>Email: Cheryl.R.Vendemia@usace.army.mil</p><p>and</p><p>Nicole Baker</p><p>Project Manager</p><p>USACE Fort Worth District </p><p>Email: Nicole.D.Baker@usace.army.mil</p><p><br></p><p><strong>Timeline for Review of Statements of Interest:</strong> RSOIs are required to be posted on www.Grants.gov for 30 days prior to the Government making a decision and requesting full proposals. </p><p><br></p><p>Refer to RSOI Package for complete details. <strong> Award is anticipated in Fiscal Year 2027. </strong></p><p><br></p>
W9126G262SOI0520
Award Ceiling
$1.7M
Closes
Oct 6, 2026
24d left
DoW Pancreatic Cancer Research Program, Translational Research Partnership Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award supports partnerships between clinicians, population scientists, applied scientists and/or basic scientists that will accelerate the movement of promising ideas in pancreatic cancer toward clinical applications. The partnership must include at least one member with expertise in pancreatic cancer research or pancreatic cancer patient care. All applications must address at least one of the <u style="color: blue;">FY26 PCARP Focus Areas</u><span style="color: black;">.</span></p> <p>· This award mechanism requires preliminary data to support feasibility of the research hypothesis(es) and research approaches. However, these data do not necessarily need to originate from studies of pancreatic cancer. Applications can support retrospective tissue analysis, correlative studies and pilot clinical trials; however, this mechanism does not allow large-scale clinical trials.</p> <p>· <strong>The Translational Research Partnership Award requires two Principal Investigators (PIs) </strong>referred to as the Initiating PI and the Partnering PI<em>. </em>Only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.</p>
HT942526PCARPTRPA
Award Ceiling
$6.6M
Closes
Oct 7, 2026
25d left
DoW Pancreatic Cancer Research Program, Focused Pilot Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Focused Pilot Award supports the exploration and development of impactful and innovative concepts under <u style="color: blue;">a patient-centered focus area</u><span style="color: blue;"> </span><span style="color: black;">of pancreatic cancer research that could ultimately lead to major advancements that will have a profound effect on patients’ overall quality of life. The research this award supports should strive to produce robust preliminary data that can serve as a foundation for future clinical or real-world research application.</span></p> <p><strong>Distinctive Features: </strong>This award mechanism allows, but does not require, preliminary data. Applications can support clinical research studies; however, this mechanism does not allow clinical trials. Preclinical animal studies do not meet the intent of this mechanism.</p>
HT942526PCARPFPTA
Award Ceiling
$1.2M
Closes
Oct 7, 2026
25d left
DoW Pancreatic Cancer Research Program, Idea Development Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for individuals with pancreatic cancer. This award mechanism supports innovative ideas with the potential to yield impactful data and new avenues of investigation. All applications must address at least one of the <span style="color: blue;">FY26 PCARP Focus Areas</span>.</p> <p><strong>Distinctive Features: </strong></p> <ul> <li>This award mechanism requires preliminary data relevant to the proposed project. Applications can support clinical research studies; however, this mechanism does not allow clinical trials.</li> <li><strong>Partnering Principal Investigator (PI) Option for Early-Career Investigator: </strong>This funding mechanism offers a higher level of funding for applications that propose to partner an experienced PI (i.e., Initiating PI, who will serve as the mentor) with an Early-Career Investigator (i.e., Partnering PI) wishing to pursue a career in pancreatic cancer research. For this option, only the Initiating PI will submit a pre-application, but both PIs will need to submit at the full application stage. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.</li> </ul>
HT942526PCARPIDA
Award Ceiling
$9.9M
Closes
Oct 7, 2026
25d left
Mathematical Foundations of Artificial Intelligence
<span class="TextRun SCXW5499492 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW5499492 BCX9">Machine Learning and Artificial Intelligence (AI) are enabling extraordinary scientific breakthroughs in fields ranging from protein folding, natural language processing, drug synthesis, and recommender </span></span>systems to the discovery of novel engineering materials and products. These achievements lie at the confluence of mathematics, statistics, engineering and computer science, yet a clear explanation of the remarkable power and also the limitations of such AI systems has eluded scientists from all disciplines. Critical foundational gaps remain that, if not properly addressed, will soon limit advances in machine learning, curbing progress in artificial intelligence. It appears increasingly unlikely that these critical gaps can be surmounted with increased computational power and experimentation alone. Deeper mathematical understanding is essential to ensuring that AI can be harnessed to meet the future needs of society and enable broad scientific discovery, while forestalling the unintended consequences of a disruptive technology. The National Science Foundation Directorates for Mathematical and Physical Sciences (MPS), Computer and Information Science and Engineering (CISE), Engineering (ENG), and Social, Behavioral and Economic Sciences (SBE) will jointly sponsor research collaborations consisting of mathematicians, statisticians, computer scientists, engineers, and social and behavioral scientists focused on the mathematical and theoretical foundations of AI. Research activities should focus on the most challenging mathematical and theoretical questions aimed at understanding the capabilities, limitations, and emerging properties of AI methods as well as the development of novel, and mathematically grounded, design and analysis principles for the current and next generation of AI approaches. <span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none">Specific research goals include: establishing a fundamental mathematical understanding of the</span><span class="TrackChangeTextInsertion TrackedChange SCXW112196119 BCX9"><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none">factors determining the </span></span><span class="TrackChangeTextInsertion TrackedChange SCXW112196119 BCX9"><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none">capabilities and limitations of</span></span><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none"> current </span><span class="TrackChangeTextInsertion TrackedChange SCXW112196119 BCX9"><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none">and emerging </span></span><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none">generation</span><span class="TrackChangeTextInsertion TrackedChange SCXW112196119 BCX9"><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none">s</span></span><span class="TextRun SCXW112196119 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="none"><span class="NormalTextRun SCXW112196119 BCX9"> of</span><span class="NormalTextRun CommentStart CommentHighlightPipeRest CommentHighlightRest SCXW112196119 BCX9"> AI systems,</span></span> including, but not limited to, foundation models, generative models, deep learning, statistical learning, federated learning, and other evolving paradigms; the development of mathematically grounded design and analysis principles for the current and next generations of AI systems; rigorous approaches for characterizing and validating machine learning algorithms and their predictions; research enabling provably reliable, translational, general-purpose AI systems and algorithms; e<span class="TextRun SCXW130074789 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="none">ncouragement of new collaborations</span><span class="TextRun SCXW130074789 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="none"> in this interdisciplinary research community and between institution</span><span class="TrackChangeTextInsertion TrackedChange SCXW130074789 BCX0"><span class="TextRun SCXW130074789 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="none">s.</span></span> The overall goal is to establish innovative and principled design and analysis approaches for AI technology using creative yet theoretically grounded mathematical and statistical frameworks, yielding explainable and interpretable models that can enable sustainable, socially responsible, and trustworthy AI. <div></div>
24-569
Award Ceiling
$1.5M
Closes
Oct 9, 2026
27d left
Algebra and Number Theory
The Algebra and Number Theory program supports research in algebra, algebraic and arithmetic geometry, number theory, and representation theory. Conference proposals<br /> The Algebra and Number Theory program also provides support for conferences, workshops, summer/winter schools, and similar activities. Proposals should be submitted to PD 20-1264 using the "Conference" proposal type in research.gov. Proposals with budgets not exceeding $50,000, which in accordance with NSF policy can be reviewed internally, should be submitted: <ul> <li>in May for events that will take place in January through April of the following year</li> <li>in October for events that will take place in May through December of the following year.</li> </ul> In order to allow time for external review, proposals with budget requests exceeding $50,000 should be submitted nine to twelve months before the event is scheduled to take place.
PD-20-1264
Award Ceiling
—
Closes
Oct 9, 2026
27d left
Research and Education Program for Historically Black Colleges and Universities (HBCU) and Tribal Colleges and Universities (TCU) Equipment/Instrumentation
<p>Under the authority of 10 U.S.C. § 4144, in alignment with Section 223 of the FY 2026 National Defense Authorization Act (NDAA), funding in the FY 2026 defense appropriations, and, Presidential Executive Order 14332, Improving Oversight of Federal Grantmaking, the DoW announces this funding opportunity for the acquisition of equipment/instrumentation at Historically Black Colleges and Universities (HBCUs) and Tribal Colleges and Universities (TCUs).</p><p><br></p><p>The program is executed under policy and guidance of the Office of the Under Secretary of War for Research and Engineering (OUSW(R&E)) and is administered by ARL, ONR, and AFOSR, hereafter called “the Agencies.”</p><p><br></p><p>This Notification of Funding Opportunity (NOFO) aims to (a) enhance research and education programs and capabilities in scientific and engineering disciplines critical to the national security functions of DoW; (b) enhance the capacity of HBCUs and TCUs to participate in DoW research programs and activities; and (c) increase the number of graduates in the fields of science, technology, engineering, and mathematics (STEM). The DoW is announcing this research solicitation based on 10 U.S.C. § 4144 and Section 223 of the FY 2026 NDAA (https://www.congress.gov/119/bills/s1071/BILLS-119s1071enr.pdf), which directs for fiscal year 2026 and each fiscal year thereafter, the Secretary of Defense to ensure that funding solicitations through the DoW HBCU/MI Program Element include separate funding solicitations each focused toward: (1) Historically Black Colleges and Universities and Tribal Colleges; and (2) Minority-Serving Institutions that are not HBCUs or TCUs. Also informing this solicitation is Section 262 of the NDAA for FY 2020 (https://www.congress.gov/116/plaws/publ92/PLAW-116publ92.pdf), section 220 of the NDAA for FY 2022 (https://www.congress.gov/117/plaws/publ81/PLAW-117publ81.pdf), and the publication of the National Academies of Sciences, Engineering, and Medicine titled “Defense Research Capacity at Historically Black Colleges and Universities and Other Minority Institutions: Transitioning from Good Intentions to Measurable Outcomes” dated April 28, 2022 (https://www.nationalacademies.org/publications/26399).</p><p><br></p><p>The DoW is soliciting applications (also referred to as “proposals”) for the acquisition of equipment/instrumentation under the Fiscal Year 2027 Research and Education Program for HBCU/MI. The Research and Education Program is designed to enhance the research capabilities of HBCUs and MIs and to strengthen their STEM education programs. The purpose of the funding under this NOFO is to (1) support the acquisition of equipment/instrumentation to augment existing capabilities or to develop new capabilities in research areas of interest to DoW, and (2) attract students to pursue studies leading to STEM careers. Although funding provided under this NOFO cannot be used for student support, in order to further DoW’s objective of attracting students to pursue studies leading to STEM careers, applicants must address the impact of the requested equipment/instrumentation on student participation in research. </p><p>The proposals must align with the research areas of interest to the DoW (which includes the USW(R&E) and the Agencies) and enhance the education of students in areas of STEM that align with the DoW research interests.</p>
W911NF26S0105
Award Ceiling
$1.5M
Closes
Oct 9, 2026
27d left
Engineering Research Initiation (ERI)
<p>The NSF Directorate for Engineering (ENG) seeks to build engineering research capacity across the nation by investing in new academic investigators who have yet to receive sufficient research funding from Federal Agencies. The Engineering Research Initiation (ERI) program will support new investigators as they initiate their research programs and advance in their careers as researchers, educators, and innovators. This funding opportunity aims to broaden the base of investigators involved in engineering research and therefore is limited to investigators that are not affiliated with “very high research activity” R1 institutions (according to the Carnegie Classification <a href="https://www.nsf.gov/cgi-bin/good-bye?https://carnegieclassifications.iu.edu/">https://carnegieclassifications.iu.edu/</a>).</p> <p> </p>
24-590
Award Ceiling
$11.0M
Closes
Oct 9, 2026
27d left
DoW Melanoma Research Program Melanoma Academy Scholar Award
<p><strong>Summary: </strong>Supports the addition of independent, <strong><em>early career investigators (Scholars)</em></strong> who are no more than seven years from their initial faculty appointment to the Melanoma Research Program (MRP) Melanoma Academy. The Melanoma Academy is a unique, interactive virtual academy focused on bringing together established investigators and Scholars to develop a network of successful, highly productive melanoma researchers in a collaborative research and career development environment.</p><p><br></p><p><strong>Distinctive Features:</strong></p><ul><li>This award mechanism focuses on both the Scholar’s research and career potential in the melanoma field.</li><li>Scholars must designate a Career Guide. The Career Guide must have a track record of successful mentorship coupled with a strong record of funding and publications <strong><em>in melanoma.</em></strong></li><li>Preliminary data are <strong><em>not required.</em></strong></li></ul>
HT942526MRPMASA
Award Ceiling
$1.5M
Closes
Oct 14, 2026
32d left
Tribal Colleges and Universities Program (TCUP)
<p>The Tribal Colleges and Universities Program (TCUP) provides awards to federally recognized<sup>1 </sup> Tribal Colleges and Universities, Alaska Native-serving institutions, and Native Hawaiian-serving institutions to promote high quality science (including sociology, psychology, anthropology, linguistics, economics and bioeconomics, statistics, and other social and behavioral sciences; natural sciences; computer science, including, but not limited to, artificial intelligence, quantum information science, and cybersecurity), technology, engineering and mathematics (STEM), STEM education, research, and outreach. Support is available to TCUP-eligible institutions (see the Additional Eligibility subsection of Section IV of this solicitation) for transformative capacity-building or community engagement projects through <strong>Instructional Capacity Excellence in TCUP Institutions (ICE-TI)</strong>, <strong>Targeted STEM Infusion Projects (TSIP)</strong>,<strong>TCUP for Secondary and Elementary Teachers in STEM (TSETS)</strong>, <strong>TCU Enterprise Advancement Centers (TEA Centers)</strong>, <strong>Cyberinfrastructure Health, Assistance, and Improvements (CHAI)</strong>, and <strong>Preparing for TCUP Implementation (Pre-TI)</strong>. Collaborations led by TCUP institutions that involve non-TCUP institutions of higher education are supported through <strong>TCUP Partnerships</strong>, with the participation of other NSF programs to support the work of non-TCUP institutions. Finally, research studies that further the scholarly activity of individual faculty members are supported through <strong>Small Grants for Research (SGR)</strong>. Through the opportunities highlighted above, as well as collaborations with other National Science Foundation (NSF) divisions and directorates, and other organizations, TCUP aims to increase Native individuals' participation in STEM careers, improve the quality of STEM programs at TCUP-eligible institutions, and facilitate the development of a strong STEM enterprise in TCUP institutions' service areas.</p> <div class="WordSection1"> <p>TCUP supports transformative capacity-building, community engagement, or research projects at TCUP-eligible institutions through the following funding tracks:</p> <p><strong>Instructional Capacity Excellence in TCUP Institutions (ICE-TI) </strong>projects provide support to design, implement, and assess comprehensive institutional improvements in STEM education and research capacity at TCUP-eligible institutions of higher education. By strengthening STEM education and STEM education research, successful projects will increase the number of STEM students and improve the quality of their preparation. ICE-TI projects create and/or adapt and assess innovative models and materials for teaching and learning in STEM, embody knowledge about how students learn most effectively in STEM teaching and learning activities, and bring STEM disciplinary advances into the undergraduate or graduate experience. The objective of this strand is to expand STEM degrees offered by TCUP-eligible institutions or significantly enhance instructional approaches.</p> <p><strong>Targeted STEM Infusion Projects (TSIP) </strong>support the attainment of a short-term, well-defined goal to improve the quality of STEM education at an eligible institution. Targeted STEM Infusion Projects could, for example, enhance academic infrastructure by systematically adding traditional knowledge to the scope or content of a STEM course, updating curricula, modernizing laboratory research equipment, developing and delivering professional development for K-12 STEM educators, or improving the computational infrastructure. The objective of this strand is to expand STEM degrees or significantly enhance instructional approaches.</p> <p><strong>TCUP for Secondary & Elementary Teachers in STEM (TSETS) </strong>supports in-service professional development in STEM disciplinary or STEM education content and/or research for K-12 STEM teachers in the relevant service area. Examples of project activities include, but are not limited to, professional development involving seminar series and engagement in STEM instruction and content during the academic year, structured series of summer intensive workshops and trainings, and summer research opportunities. The objective of this strand is to broaden the instructional capacity for STEM in the K-12 workforce and thereby to the entire community, and to build the capacity for STEM disciplinary or education research among participating educational professionals. </p> <p><strong>TCU Enterprise Advancement Centers (TEA Centers) </strong>coalesce the STEM and/or STEM education expertise into a team, designed to support and promote the STEM goals, needs, aspirations, or interests of the chartering reservation or tribe(s). TEA Centers may address a critical tribal or community need or focus on a realm of research or design that is beyond the scope of individual research grants or that is of interest to multiple tribes. The objective of this strand is to build on the capacity developed through prior TCUP support and apply expertise to collaborations with communities in the institution’s service area, or nationally. </p> <p>The <strong>Cyberinfrastructure Health, Assistance, and Improvements (CHAI) </strong>strand supports projects at TCUP-eligible institutions of higher education to upgrade the cyberinfrastructure necessary to conduct, expand, manage and administer STEM programs of study, including research. The objective of this strand is to equip TCUP institutions to meet the demands of virtual instruction, advanced computing, and data science opportunities. </p> <p><strong>Preparing for TCUP Implementation (Pre-TI) </strong>provides support for activities that prepare an institution for Implementation-level projects. Consequently, they are available only to TCUP-eligible institutions of higher education that have never received TCUP support, have not received TCUP support within the previous five years, or are embarking on a significantly novel STEM strategic plan. Examples of supported activities include completing an institutional assessment of its current STEM instructional capacity, or engaging in conversations necessary to formulate a shared vision of what that capacity should be and how to achieve it. Pre-TI awards can support staff and faculty release time, travel, stakeholder gatherings, and associated administrative costs. The objective of this strand is to conduct self-studies and formulate strategic plans for the development of STEM instructional programs of study. </p> <p>The <strong>TCUP Partnerships </strong>strand provides support for collaborations that will improve TCUP institutions' instructional and research capacity in STEM fields supported by NSF; attract, retain, and support TCUP students in internships and research endeavors deemed to be necessary for a complete curriculum offering; and engage partner universities to provide an academic grounding and a successful transition for students who wish to study or attain degrees in STEM fields supported by NSF. TCUP Partnerships broaden the number of scientific disciplines available to students at TCUP institution through collaborations with non-TCUP institutions. Active Pre-Engineering Education Collaboratives or Partnerships in Geoscience Education awards are not affected by this revision. The objective of this strand is the development, through instructional and research capacity-building, of academic and career pathways for TCUP students through supporting collaborative projects between and among TCUP and non-TCUP institutions. Interested teams of collaborators for which a TCUP institution serves as lead should contact the TCUP program directors. Support for non-TCUP partners must be obtained from other NSF programs, which follows the procedures of the prior Partnership strands.</p> <p><strong>Small Grants for Research (SGR) </strong>strand support STEM or STEM Education faculty members at TCUP-eligible institutions to initiate or pursue research projects or programs that may include undergraduate or graduate student engagement. Awards are intended to help further the faculty member's research capability and effectiveness; improve research and teaching at his or her home institution and create and study new models and innovations in STEM teaching and learning. International research or collaborations are strongly encouraged. TCUP students may seek support for international research opportunities under the guidance of a TCUP STEM or STEM education faculty member and an international research collaborator. These awards are particularly appropriate as a means of recruiting and retaining highly qualified scientists, engineers, and educators at TCUP-eligible institutions. The objective of this strand is to support faculty research and professional development that build research capacity at TCUP institutions.</p> </div> <p>[1] Executive Order 13021 defines Tribal Colleges and Universities ("tribal colleges") as those institutions cited in section 532 of the Equity in Educational Land-Grant Status Act of 1994 (7 U.S.C. 301 note), and other institutions that qualify for funding under the Tribally Controlled Community College Assistance Act of 1978, (25 U.S.C. 1801 et seq.), as well as Navajo Community College as authorized in the Navajo Community College Assistance Act of 1978, Public Law 95-471, Title II (25 U.S.C. 640a note). The term "Alaska Native-serving institution" means an institution of higher education that is an eligible institution under section 1058(b) of the Higher Education Act; and that, at the time of submission, has an undergraduate enrollment that is at least 20 percent Alaska Native students. The term "Native Hawaiian-serving institution" means an institution of higher education that is an eligible institution under section 1058(b) of the Higher Education Act; and that, at the time of submission, has an undergraduate enrollment that is at least 10 percent Native Hawaiian students. Most TCUP-eligible institutions of higher education are two-year or community colleges. See the Who May Submit Proposals section in this solicitation for further details.</p>
21-595
Award Ceiling
$3.5M
Closes
Oct 14, 2026
32d left
Mathematical Biology
The Mathematical Biology Program supports research in all areas of mathematical sciences with relevance to the biological sciences. Successful proposals must demonstrate mathematical innovation, biological relevance and significance, and strong integration between mathematics and biology. Some projects of interest to the Mathematical Biology Program may include development of mathematical theories, methodologies, and tools traditionally seen in other disciplinary programs within the Division of Mathematical Sciences. In general, if a proposal is appropriate for review by more than one NSF program, it is advisable to contact the program officers handling each program to determine when and where the proposal should be submitted and to facilitate the review process. The Mathematical Biology Program regularly seeks joint reviews of proposals with programs in the Directorates of Biological Sciences and other relevant programs. Investigators are encouraged to discuss their project with program officers in relevant areas to determine whether it could be considered by more than one program. Research in Undergraduate Institutions (RUI) Investigators submitting an RUI proposal should read the RUI solicitation (link below), as the rules for proposal format may deviate from the Proposal & Award Policies & Procedures Guide (PAPPG). EAGER and RAPID Proposals Prior to submitting proposals for EArly-concept Grants for Exploratory Research (EAGER) or Rapid Response Research (RAPID), Investigators must contact the cognizant program directors. Requests for Award Supplements Principal Investigatorsare encouraged to contact the cognizant program director prior to submission of a proposal for an award supplement. See the PAPPG for more information. Conferences Investigators should carefully read the program solicitation, "Conferences and Workshops in the Mathematical Sciences," (link below) to obtain important information regarding the substance of proposals for conferences, workshops, summer/winter schools, and similar activities. To facilitate timely notification of the availability of support: <ul> <li>proposals for conferences, workshops, etc., to be held in the US must be submitted 8 months in advance of the conference date;</li> <li>proposals to support group travel to meetings outside the US must be submitted 12 months in advance of the meeting date.</li> </ul>
PD-22-7334
Award Ceiling
—
Closes
Oct 14, 2026
32d left
DoW Melanoma Research Program Team Science Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Team Science Award supports a broad range of hypothesis-driven, multidisciplinary studies that have a short-term goal of advancing the state of the science in melanoma research and/or patient care. Team science is a synergistic effort that harnesses techniques, approaches and perspectives from multiple disciplines and/or therapeutic areas to address complex, multi-dimensional problems that will impact patient outcomes.</p> <p><strong>Distinctive Features:</strong></p> <p><strong>· This funding mechanism requires multiple Principal Investigators (PIs). At least two and up to three PIs should partner to jointly design and execute <em>a single research project</em></strong>; multi-institutional partnerships are encouraged. If recommended for funding, each PI will be named on separate awards to the recipient organization(s).</p> <p><span style="color: black;">· </span><strong>Consumer Collaboration Option: </strong>Investigators are encouraged, but not required, to form collaborative relationships with the <u style="color: blue;">melanoma consumer community</u><span style="color: blue;"> </span><span style="color: black;">to maximize the impact and translatability of the research for the benefit of the intended community(ies).</span></p> <p><strong>· After submitting the required pre-application, <em>investigators must receive an invitation to submit a full application</em></strong>.</p> <ul> <li><span style="color: black;"> </span>Only the Initiating PI will submit a pre-application. All PIs <strong><em>must </em></strong>submit full applications. The <u style="color: blue;">Partnering PI(s)’s application</u><span style="color: blue;"> </span><span style="color: black;">is an abbreviated package specific to their proposed research effort.</span></li> </ul> <p><br></p>
HT942526MRPTSA
Award Ceiling
$18.9M
Closes
Oct 14, 2026
32d left
DoW Melanoma Research Program Survivorship Research Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Survivorship Research Award addresses the relatively new and underfunded area of melanoma-specific survivorship by supporting a broad range of innovative and impactful research that has the intended outcome of improving the health and well-being of melanoma survivors, their families and/or their care partners in the near term. Proposed studies focusing exclusively on animal models or considering survival only without consideration of quality of life, overall health and/or function are not responsive to this funding opportunity.</p> <p><strong>Distinctive Features:</strong></p> <p><span style="color: black;">· </span>The application <strong><em>must </em></strong>include at least one <u style="color: blue;">melanoma consumer collaborator</u><span style="color: black;">, defined as a melanoma survivor, family member and/or care partner who can provide lived experience expertise to the research project team, or a melanoma-community supporting organization to support the planning, execution, and implementation of the proposed research.</span></p> <p><strong style="background-color: lightgrey;">· Clinical trials </strong><strong><em>are </em></strong>allowed.</p> <p><br></p>
HT942526MRPSRA
Award Ceiling
$2.0M
Closes
Oct 14, 2026
32d left
DoW Melanoma Research Program Idea Award
<p><strong>Summary: </strong>The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Idea Award supports innovative, exploratory, high-risk/potentially high-reward research. Novelty and innovation are expected to be key aspects of the proposed project. By the end of the Idea Award funding period, the anticipated outcomes of successful efforts should establish proof of principle and obtain preliminary data to secure follow-on funding.</p><p><br></p><p><strong>Distinctive Features:</strong></p><p> • Preliminary data are<strong><em> discouraged.</em></strong></p><p> • After submitting the required pre-application,<strong><em> investigators must receive an invitation to submit a full application.</em></strong></p>
HT942526MRPIA
Award Ceiling
$5.6M
Closes
Oct 14, 2026
32d left